Leuphasyl (Pentapeptide-18)
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Leuphasyl is a pentapeptide that mimics the mechanism of enkephalins at the presynaptic membrane of neuromuscular junctions. By binding to the enkephalin receptor on nerve cells, it inhibits neuronal activity, reducing the release of catecholamines and acetylcholine. This decreases muscle contraction intensity around expression lines, providing a 'Botox-like' wrinkle relaxation effect. It shows synergistic effects when combined with Argireline (Acetyl Hexapeptide-3), enhancing anti-wrinkle activity up to an additional 25%.
| Level | Amount | Frequency | Timing |
|---|---|---|---|
| Beginner | 2% concentration topical | Once daily | Evening application to expression-prone areas |
| Standard | 5% concentration topical | Twice daily | Morning and evening after cleansing |
| Advanced | 5-10% combined with Argireline | Twice daily | Layered application for synergistic effects |
Ongoing daily use; visible results in 2-4 weeks
Topical - sustained release at application site
Dissolve in cosmetic-grade water or serum base for topical use
Store at 36-46°F, protect from light
Room temperature in formulation, use within expiry
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Evidence-based supplement analysis
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This information is provided for educational and research purposes only. It is not intended as medical advice, diagnosis, or treatment recommendation. Consult a licensed healthcare professional before using any peptide. BioProtocol does not sell peptides or pharmaceutical products.