Semax

Semax (ACTH 4-10 Analog)

Cognitive

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From $37.99

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Limitless Life Nootropics
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US, International
$37.99
$7.60/mg

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Mechanism of Action

Semax is a synthetic heptapeptide derived from ACTH (4-10) that upregulates BDNF and related neurotrophic factors, enhances dopaminergic and serotonergic pathways, provides neuroprotection through anti-inflammatory and antioxidant effects, improves cerebral blood flow and oxygen utilization, and does not stimulate cortisol release unlike native ACTH.

Primary Benefits

  • Enhances focus and attention
  • Improves memory and learning
  • Increases mental stamina
  • Reduces anxiety
  • Improves mood
  • Neuroprotective effects
  • Enhances stress resilience
  • Supports stroke recovery

Common Uses

  • Cognitive enhancement
  • ADHD support
  • Stroke recovery
  • Traumatic brain injury
  • Anxiety reduction
  • Mental fatigue
  • Neuroprotection

Side Effects

  • Nasal irritation (intranasal use)
  • Mild headache
  • Restlessness (high doses)
  • Mild fatigue
  • Minimal side effects overall

Contraindications

  • Active psychotic disorders
  • Severe psychiatric instability
  • Pregnancy and breastfeeding
  • Known hypersensitivity

Dosage Protocols

LevelAmountFrequencyTiming
Beginner250-300 mcg1-2 times dailyMorning and early afternoon (intranasal)
Standard300-600 mcg1-3 times dailyMorning and early afternoon (intranasal)
Advanced600-900 mcg2-3 times dailyMorning and early afternoon (intranasal)

Cycle Duration

5-14 days, with 1-3 month breaks

Half-Life

Approximately 20-30 minutes

Reconstitution Instructions

Intranasal spray (0.1% solution) - no reconstitution needed

Storage Requirements

Unreconstituted (Powder):

Refrigerate at 36-46°F

Reconstituted:

Refrigerate at 36-46°F, protect from light

Research & Literature

Explore peer-reviewed studies and clinical research on Semax

Research Disclaimer: These links lead to external research databases. Always consult with a qualified healthcare provider before making decisions based on research literature.

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For Research Purposes Only

This information is provided for educational and research purposes only. It is not intended as medical advice, diagnosis, or treatment recommendation. Consult a licensed healthcare professional before using any peptide. BioProtocol does not sell peptides or pharmaceutical products.