Semaglutide (GLP-1 Receptor Agonist)
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Semaglutide is a GLP-1 receptor agonist that mimics natural GLP-1 hormone. It increases glucose-dependent insulin secretion, suppresses glucagon release, delays gastric emptying to reduce post-meal glucose spikes, and activates brain receptors to increase satiety and reduce appetite. Structural modifications provide resistance to DPP-4 degradation and albumin binding for extended half-life.
| Level | Amount | Frequency | Timing |
|---|---|---|---|
| Beginner | 0.25 mg | Once weekly | Any day, same time each week |
| Standard | 1.0 mg | Once weekly | Titrate from 0.25mg over 4-8 weeks |
| Advanced | 2.4 mg | Once weekly | For weight management, titrate gradually |
Long-term use under medical supervision
Approximately 1 week
Pre-filled pens, no reconstitution needed
N/A - comes as pre-filled pen
Refrigerate at 36-46°F, protect from light
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