Melanotan II

Melanotan II (MT-II)

Sexual Function

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From $34.99

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PekCura Labs
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US, Canada, EU3rd Party TestedCOA
$34.99
$3.50/mg
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Biotech Peptides
US, InternationalJanoshik AnalyticalCOA
$42.99
$4.30/mg
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Prices shown are approximate and may vary. Click vendor links for current pricing. Links may be affiliate links — we may earn a small commission at no extra cost to you. Prices last checked Mar 29, 2026.

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Mechanism of Action

Melanotan II is a synthetic analog of alpha-MSH that binds to melanocortin receptors (MC1R, MC3R, MC4R, MC5R). MC1R activation stimulates melanogenesis for tanning, MC4R activation in the hypothalamus enhances libido and erectile function, MC3R modulation affects appetite and energy balance.

Primary Benefits

  • ✓Promotes skin tanning without UV
  • ✓Enhances libido and sexual function
  • ✓Supports erectile function
  • ✓May reduce appetite
  • ✓Provides UV protection via melanin
  • ✓Potential fat loss effects

Common Uses

  • •Sunless tanning
  • •Erectile dysfunction support
  • •Low libido treatment
  • •Skin protection from UV damage
  • •Body composition improvement

Side Effects

  • ⚠Nausea (common initially)
  • ⚠Facial flushing
  • ⚠Fatigue
  • ⚠Spontaneous erections
  • ⚠Darkening of moles
  • ⚠Appetite suppression
  • ⚠Yawning and stretching

Contraindications

  • ✕History of melanoma or skin cancer
  • ✕Multiple atypical moles
  • ✕Pregnancy and breastfeeding
  • ✕Cardiovascular disease
  • ✕Severe hypertension

Dosage Protocols

LevelAmountFrequencyTiming
Beginner100-250 mcgEvery other dayEvening to minimize nausea
Standard250-500 mcgDaily during loading, then 1-2x weeklyLoading phase 2-3 weeks, then maintenance
Advanced500-1000 mcgDaily during loading phaseWith minimal UV exposure for best results

Cycle Duration

Loading: 2-3 weeks daily, Maintenance: Indefinite with 1-2 weekly doses

Half-Life

33-36 minutes (effects last 6-8 hours)

Reconstitution Instructions

Add bacteriostatic water slowly, gently swirl until clear

Storage Requirements

Unreconstituted (Powder):

Refrigerate at 36-46°F or freeze, protect from light

Reconstituted:

Refrigerate at 36-46°F, use within 28 days

Research & Literature

Explore peer-reviewed studies and clinical research on Melanotan II

PubMed

Peer-reviewed medical research

ClinicalTrials.gov

Active and completed clinical trials

Google Scholar

Academic papers and citations

Examine.com

Evidence-based supplement analysis

Research Disclaimer: These links lead to external research databases. Always consult with a qualified healthcare provider before making decisions based on research literature.

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For Research Purposes Only

This information is provided for educational and research purposes only. It is not intended as medical advice, diagnosis, or treatment recommendation. Consult a licensed healthcare professional before using any peptide. BioProtocol does not sell peptides or pharmaceutical products.