KPV

Lysine-Proline-Valine Tripeptide

Healing

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From $39.00

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Biotech Peptides
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US, InternationalJanoshik AnalyticalCOA
$39.00
$9.75/mg
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Mechanism of Action

KPV is a C-terminal tripeptide fragment of alpha-MSH that inhibits NF-κB activation, reduces pro-inflammatory cytokines (IL-1β, IL-6, TNF-α), modulates gut microbiome, strengthens intestinal barrier function, and provides antimicrobial effects against various pathogens including bacteria and fungi.

Primary Benefits

  • ✓Reduces gut inflammation
  • ✓Heals intestinal lining
  • ✓Supports IBD and IBS management
  • ✓Antimicrobial properties
  • ✓Wound healing enhancement
  • ✓Modulates immune response
  • ✓Reduces allergic responses
  • ✓Supports skin healing

Common Uses

  • •Inflammatory bowel disease (IBD)
  • •Irritable bowel syndrome (IBS)
  • •Leaky gut syndrome
  • •Chronic gut inflammation
  • •Post-antibiotic gut restoration
  • •Skin conditions and wound healing

Side Effects

  • ⚠Generally well-tolerated
  • ⚠Mild injection site reaction
  • ⚠Temporary fatigue
  • ⚠Mild gastrointestinal changes

Contraindications

  • ✕Pregnancy and breastfeeding
  • ✕Active infections requiring antibiotics
  • ✕Immunosuppressive conditions

Dosage Protocols

LevelAmountFrequencyTiming
Beginner200-400 mcgOnce dailyMorning or evening, on empty stomach
Standard500 mcgOnce or twice dailySplit doses morning and evening
Advanced750-1000 mcgTwice dailyMorning and before bed

Cycle Duration

4-12 weeks depending on condition severity

Half-Life

15-30 minutes (frequent dosing recommended)

Reconstitution Instructions

Add bacteriostatic water slowly, gently swirl until dissolved

Storage Requirements

Unreconstituted (Powder):

Refrigerate at 36-46°F, protect from light

Reconstituted:

Refrigerate at 36-46°F, use within 21 days

Research & Literature

Explore peer-reviewed studies and clinical research on KPV

PubMed

Peer-reviewed medical research

ClinicalTrials.gov

Active and completed clinical trials

Google Scholar

Academic papers and citations

Examine.com

Evidence-based supplement analysis

Research Disclaimer: These links lead to external research databases. Always consult with a qualified healthcare provider before making decisions based on research literature.

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For Research Purposes Only

This information is provided for educational and research purposes only. It is not intended as medical advice, diagnosis, or treatment recommendation. Consult a licensed healthcare professional before using any peptide. BioProtocol does not sell peptides or pharmaceutical products.