Kisspeptin-10

Kisspeptin-10 (Metastin)

Sexual Function

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Pricing data is updated regularly.

Mechanism of Action

Kisspeptin-10 activates the GPR54 receptor in hypothalamic GnRH neurons, triggering the release of gonadotropin-releasing hormone (GnRH). This cascade stimulates LH and FSH release from the pituitary, which then promotes testosterone/estrogen production. It's the master regulator of the reproductive axis.

Primary Benefits

  • Stimulates natural testosterone production
  • Enhances LH and FSH release
  • Supports fertility in both sexes
  • Restores reproductive axis function
  • May enhance libido
  • Supports post-cycle recovery

Common Uses

  • Testosterone optimization
  • Male fertility support
  • Female fertility treatments
  • Post-cycle therapy (PCT)
  • Hypogonadism support
  • Libido enhancement

Side Effects

  • Injection site irritation
  • Temporary flushing
  • Headache
  • Mild nausea
  • Emotional fluctuations

Contraindications

  • Hormone-sensitive cancers
  • Pregnancy (except under supervision)
  • Severe kidney or liver disease
  • Uncontrolled hypertension

Dosage Protocols

LevelAmountFrequencyTiming
Beginner50-100 mcgOnce dailyMorning administration
Standard100-200 mcgOnce or twice dailyMorning and/or evening
Advanced200-400 mcgTwice dailySplit doses, 8-12 hours apart

Cycle Duration

4-8 weeks for PCT, longer for fertility support

Half-Life

27 minutes (multiple daily doses needed)

Reconstitution Instructions

Add bacteriostatic water slowly, gently swirl

Storage Requirements

Unreconstituted (Powder):

Refrigerate at 36-46°F or freeze, protect from light

Reconstituted:

Refrigerate at 36-46°F, use within 14 days

Research & Literature

Explore peer-reviewed studies and clinical research on Kisspeptin-10

Research Disclaimer: These links lead to external research databases. Always consult with a qualified healthcare provider before making decisions based on research literature.

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For Research Purposes Only

This information is provided for educational and research purposes only. It is not intended as medical advice, diagnosis, or treatment recommendation. Consult a licensed healthcare professional before using any peptide. BioProtocol does not sell peptides or pharmaceutical products.