Humanin

Humanin Mitochondrial-Derived Peptide

Anti Aging

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Mechanism of Action

Humanin is a 24-amino acid mitochondrial-derived peptide that provides cytoprotection against oxidative stress and apoptosis. It binds to IGFBP-3 and BAX, inhibits amyloid-beta toxicity, enhances insulin sensitivity, reduces inflammation, and protects against age-related cellular damage through multiple signaling pathways.

Primary Benefits

  • ✓Cellular protection against stress
  • ✓Neuroprotection
  • ✓Anti-apoptotic effects
  • ✓Improved insulin sensitivity
  • ✓Cardiovascular protection
  • ✓Anti-aging at cellular level

Common Uses

  • •Anti-aging protocols
  • •Cognitive support
  • •Metabolic health
  • •Cardiovascular health
  • •Longevity optimization
  • •Neuroprotection

Side Effects

  • ⚠Limited human data available
  • ⚠Potential injection site reactions
  • ⚠Mild fatigue initially

Contraindications

  • ✕Pregnancy and breastfeeding
  • ✕Active malignancy
  • ✕Autoimmune conditions (use with caution)

Dosage Protocols

LevelAmountFrequencyTiming
Beginner1-2 mgOnce dailyMorning, subcutaneous
Standard2-4 mgOnce dailyMorning or evening
Advanced4-5 mgOnce dailyConsistent timing each day

Cycle Duration

8-12 weeks, ongoing for longevity protocols

Half-Life

~30 minutes (effects persist longer)

Reconstitution Instructions

Add bacteriostatic water slowly, swirl gently

Storage Requirements

Unreconstituted (Powder):

Freeze at -4°F for long-term

Reconstituted:

Refrigerate at 36-46°F, use within 21 days

Research & Literature

Explore peer-reviewed studies and clinical research on Humanin

PubMed

Peer-reviewed medical research

ClinicalTrials.gov

Active and completed clinical trials

Google Scholar

Academic papers and citations

Examine.com

Evidence-based supplement analysis

Research Disclaimer: These links lead to external research databases. Always consult with a qualified healthcare provider before making decisions based on research literature.

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For Research Purposes Only

This information is provided for educational and research purposes only. It is not intended as medical advice, diagnosis, or treatment recommendation. Consult a licensed healthcare professional before using any peptide. BioProtocol does not sell peptides or pharmaceutical products.