GHK

Glycyl-L-Histidyl-L-Lysine

Anti Aging

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Mechanism of Action

GHK is a naturally occurring tripeptide that declines with age. It activates over 4,000 genes related to tissue remodeling, stimulates collagen and elastin synthesis, reduces inflammation through NF-κB modulation, enhances antioxidant enzyme activity, promotes wound healing, and supports stem cell function. It is the base peptide for GHK-Cu.

Primary Benefits

  • ✓Stimulates collagen production
  • ✓Tissue remodeling support
  • ✓Anti-inflammatory effects
  • ✓Wound healing acceleration
  • ✓Gene expression regulation
  • ✓Antioxidant support

Common Uses

  • •Skin rejuvenation
  • •Wound healing
  • •Anti-aging protocols
  • •Hair growth support
  • •Tissue repair
  • •General regeneration

Side Effects

  • ⚠Minimal side effects
  • ⚠Rare skin irritation (topical)
  • ⚠Injection site reactions

Contraindications

  • ✕Active cancer (theoretical concern)
  • ✕Pregnancy and breastfeeding
  • ✕Copper sensitivity (for GHK-Cu)

Dosage Protocols

LevelAmountFrequencyTiming
Beginner100-200 mcgOnce dailySubcutaneous injection, morning
Standard200-500 mcgOnce dailyMorning or evening
Advanced500-1000 mcgOnce dailyConsistent daily timing

Cycle Duration

4-12 weeks, can be used long-term

Half-Life

~1 hour

Reconstitution Instructions

Add bacteriostatic water slowly, swirl gently

Storage Requirements

Unreconstituted (Powder):

Refrigerate or freeze

Reconstituted:

Refrigerate at 36-46°F, use within 28 days

Research & Literature

Explore peer-reviewed studies and clinical research on GHK

PubMed

Peer-reviewed medical research

ClinicalTrials.gov

Active and completed clinical trials

Google Scholar

Academic papers and citations

Examine.com

Evidence-based supplement analysis

Research Disclaimer: These links lead to external research databases. Always consult with a qualified healthcare provider before making decisions based on research literature.

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For Research Purposes Only

This information is provided for educational and research purposes only. It is not intended as medical advice, diagnosis, or treatment recommendation. Consult a licensed healthcare professional before using any peptide. BioProtocol does not sell peptides or pharmaceutical products.